Alternative Splicing

Alternative splicing is the main mechanism allowing to increase the proteome diversity encoded by a small number of genes. More than 90% of human genes produce different transcripts with different exon content.

Understanding of mechanisms involved in splicing and its regulation is important from the basic research point of view, but also for biomedical research since alteration of splicing regulation is a common characteristic of cancer and is the origin of many human diseases.

To learn more about splicing, visit the EURASNET website.

GenoSplice is the Official Service Provider of EURASNET, the European Network of Excellence on Alternative Splicing (gathering 41 research teams from 11 European countries, as well as the USA, Israel and Argentina). According to the Genetics Society, GenoSplice is “demystifying alternative splicing bioinformatics” (Genetics Society News, July 2008).

 

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