News & Events

In Eur J Hum Genet : Detecting splicing patterns in genes involved in hereditary breast and ovarian cancer

“Detecting splicing patterns in genes involved in hereditary breast and ovarian cancer.”

Davy G, Rousselin A, Goardon N, Castéra L, Harter V, Legros A, Muller E, Fouillet R, Brault B, Smirnova AS, Lemoine F, de la Grange P, Guillaud-Bataille M, Caux-Moncoutier V, Houdayer C, Bonnet F, Blanc-Fournier C, Gaildrat P, Frebourg T, Martins A, Vaur D, Krieger S.

Eur J Hum Genet. 2017 Oct 25

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In Cancer Res: Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA

“Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA.”

Jdey W, Thierry S, Popova T, Stern MH, Dutreix M.

Cancer Res. 2017 Aug 15

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In Sci Rep : Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness

“Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness.”

Sharma S, Maras JS, Das S, Hussain S, Mishra AK, Shasthry SM, Sharma CB, Weiss E, Elkrief L, Rautou PE, Gilgenkrantz H, Lotersztajn S, Paradis V, de la Grange P, Junot C, Moreau R, Sarin SK.

Sci Rep. 2017 Jul 28

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GenoSplice in pole-nsl.org

Article regarding big data in pole-nsl.org
View (in French) at:

Big data : Pourquoi l’industrie pharmaceutique va devoir changer

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Nucleic Acids Res: Alternative splicing of CNOT7 diversifies CCR4-NOT functions

“Alternative splicing of CNOT7 diversifies CCR4-NOT functions.”

Chapat C, Chettab K, Simonet P, Wang P, De La Grange P, Le Romancer M, Corbo L.

Nucleic Acids Res. 2017 Jun 07

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In Cell Discovery: Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface

“Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface.”

Boulay AC, Saubamea B, Adam N, Chasseigneaux S, Mazare N, Gilbert A, Bahin M, Bastianelli L, Blugeon C, Perrin S, Pouch J, Ducos B, Le Crom S, Genovesio A, Chretien F, Decleves X, Laplanche JL, Cohen-Salmon M.

Cell Discov. 2017 Mar 28

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GenoSplice is proud to announce its recent publication in Developmental Cell: An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation

“An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.”

Naro C, Jolly A, Di Persio S, Bielli P, Setterblad N, Alberdi AJ, Vicini E, Geremia R, de la Grange P, Sette C
Dev Cell. 2017 Mar

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In Int J Obes (Lond).: “Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice.”

“Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice.”

Santo J, Lopez-Herrera C, Apolit C, Bareche Y, Lapasset L, Chavey C, Capozi S, Mahuteau-Betzer F, Najman R, Fornarelli P, Lopez-Mejía IC, Béranger G, Casas F, Amri EZ, Pau B, Scherrer D, Tazi J.

Int J Obes (Lond). 2017 Mar

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In Proc Natl Acad Sci U S A.: “Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.”

“Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.”

Schaller S, Buttigieg D, Alory A, Jacquier A, Barad M, Merchant M, Gentien D, de la Grange P, Haase G.

Proc Natl Acad Sci U S A. 2017 Mar 7

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J Hepatol.: “Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.”

“Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.”

Weiss E, Rautou PE, Fasseu M, Giabicani M, de Chambrun M, Wan J, Minsart C, Gustot T, Couvineau A, Maiwall R, Hurtado-Nedelec M, Pilard N, Lebrec D, Valla D, Durand F, de la Grange P, Monteiro RC, Paugam-Burtz C, Lotersztajn S, Moreau R.

J Hepatol. 2016 Dec 28

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