News & Events

In Nat Commun : Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane

“Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane..”

Glentis A, Oertle P, Mariani P, Chikina A, El Marjou F, Attieh Y, Zaccarini F, Lae M, Loew D, Dingli F, Sirven P, Schoumacher M, Gurchenkov BG, Plodinec M, Vignjevic DM.

Nat Commun. 2017 Oct 13

Pubmed

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In Nucleic Acids Res : hnRNPM guides an alternative splicing program in response to inhibition of the PI3K/AKT/mTOR pathway in Ewing sarcoma cells

“hnRNPM guides an alternative splicing program in response to inhibition of the PI3K/AKT/mTOR pathway in Ewing sarcoma cells.”

Passacantilli I, Frisone P, De Paola E, Fidaleo M, Paronetto MP.

Nucleic Acids Res. 2017 Oct 3

Pubmed

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In Med Sci : Neurotrophic factors for motor neurons: an à la carte menu

“Neurotrophic factors for motor neurons: an à la carte menu.”

Alory A, Jacquier A, Gentien D, de la Grange P, Haase G.

Med Sci. 2017 Oct

Pubmed

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GenoSplice presentation at the “3ème édition des Journées Scientifiques Innovations Technologiques”

GenoSplice presentation about single cell RNA-Seq bioinformatics analysis: https://webcast.in2p3.fr/container/3eme-edition-des-journees-scientifiques-innovations-technologiques

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GenoSplice at Station F!

GenoSplice offices are now located at Station F, the world’s biggest startup campus

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In Eur J Hum Genet : Detecting splicing patterns in genes involved in hereditary breast and ovarian cancer

“Detecting splicing patterns in genes involved in hereditary breast and ovarian cancer.”

Davy G, Rousselin A, Goardon N, Castéra L, Harter V, Legros A, Muller E, Fouillet R, Brault B, Smirnova AS, Lemoine F, de la Grange P, Guillaud-Bataille M, Caux-Moncoutier V, Houdayer C, Bonnet F, Blanc-Fournier C, Gaildrat P, Frebourg T, Martins A, Vaur D, Krieger S.

Eur J Hum Genet. 2017 Oct 25

Pubmed

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In Cancer Res: Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA

“Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA.”

Jdey W, Thierry S, Popova T, Stern MH, Dutreix M.

Cancer Res. 2017 Aug 15

Pubmed

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In Sci Rep : Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness

“Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness.”

Sharma S, Maras JS, Das S, Hussain S, Mishra AK, Shasthry SM, Sharma CB, Weiss E, Elkrief L, Rautou PE, Gilgenkrantz H, Lotersztajn S, Paradis V, de la Grange P, Junot C, Moreau R, Sarin SK.

Sci Rep. 2017 Jul 28

Pubmed

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GenoSplice in pole-nsl.org

Article regarding big data in pole-nsl.org
View (in French) at:

Big data : Pourquoi l’industrie pharmaceutique va devoir changer

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Nucleic Acids Res: Alternative splicing of CNOT7 diversifies CCR4-NOT functions

“Alternative splicing of CNOT7 diversifies CCR4-NOT functions.”

Chapat C, Chettab K, Simonet P, Wang P, De La Grange P, Le Romancer M, Corbo L.

Nucleic Acids Res. 2017 Jun 07

Pubmed

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