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GenoSplice in pole-nsl.org

Article regarding big data in pole-nsl.org
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Big data : Pourquoi l’industrie pharmaceutique va devoir changer

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Nucleic Acids Res: Alternative splicing of CNOT7 diversifies CCR4-NOT functions

“Alternative splicing of CNOT7 diversifies CCR4-NOT functions.”

Chapat C, Chettab K, Simonet P, Wang P, De La Grange P, Le Romancer M, Corbo L.

Nucleic Acids Res. 2017 Jun 07

Pubmed

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In Cell Discovery: Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface

“Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface.”

Boulay AC, Saubamea B, Adam N, Chasseigneaux S, Mazare N, Gilbert A, Bahin M, Bastianelli L, Blugeon C, Perrin S, Pouch J, Ducos B, Le Crom S, Genovesio A, Chretien F, Decleves X, Laplanche JL, Cohen-Salmon M.

Cell Discov. 2017 Mar 28

Pubmed

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GenoSplice is proud to announce its recent publication in Developmental Cell: An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation

“An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.”

Naro C, Jolly A, Di Persio S, Bielli P, Setterblad N, Alberdi AJ, Vicini E, Geremia R, de la Grange P, Sette C
Dev Cell. 2017 Mar

Pubmed

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In Int J Obes (Lond).: “Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice.”

“Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice.”

Santo J, Lopez-Herrera C, Apolit C, Bareche Y, Lapasset L, Chavey C, Capozi S, Mahuteau-Betzer F, Najman R, Fornarelli P, Lopez-Mejía IC, Béranger G, Casas F, Amri EZ, Pau B, Scherrer D, Tazi J.

Int J Obes (Lond). 2017 Mar

Pubmed

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In Proc Natl Acad Sci U S A.: “Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.”

“Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.”

Schaller S, Buttigieg D, Alory A, Jacquier A, Barad M, Merchant M, Gentien D, de la Grange P, Haase G.

Proc Natl Acad Sci U S A. 2017 Mar 7

Pubmed

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J Hepatol.: “Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.”

“Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.”

Weiss E, Rautou PE, Fasseu M, Giabicani M, de Chambrun M, Wan J, Minsart C, Gustot T, Couvineau A, Maiwall R, Hurtado-Nedelec M, Pilard N, Lebrec D, Valla D, Durand F, de la Grange P, Monteiro RC, Paugam-Burtz C, Lotersztajn S, Moreau R.

J Hepatol. 2016 Dec 28

Pubmed

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Med Sci (Paris).: “Deregulation of pre-messenger RNA splicing and rare diseases.”

“Deregulation of pre-messenger RNA splicing and rare diseases.”

de la Grange P.

Med Sci (Paris). 2016 Dec

Pubmed

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Neuron.: “Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity.”

“Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity.”

Mauger O, Lemoine F, Scheiffele P.

Neuron. 2016 Nov 21

Pubmed

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Elife.: “Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3′-end processing.”

“Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3′-end processing.”

La Rosa P, Bielli P, Compagnucci C, Cesari E, Volpe E, Farioli Vecchioli S, Sette C.

Elife. 2016 Nov 15

Pubmed

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