News & Events

“Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA.”

Jdey W, Thierry S, Popova T, Stern MH, Dutreix M.

Cancer Res. 2017 Aug 15

Pubmed

“Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness.”

Sharma S, Maras JS, Das S, Hussain S, Mishra AK, Shasthry SM, Sharma CB, Weiss E, Elkrief L, Rautou PE, Gilgenkrantz H, Lotersztajn S, Paradis V, de la Grange P, Junot C, Moreau R, Sarin SK.

Sci Rep. 2017 Jul 28

Pubmed

“Alternative splicing of CNOT7 diversifies CCR4-NOT functions.”

Chapat C, Chettab K, Simonet P, Wang P, De La Grange P, Le Romancer M, Corbo L.

Nucleic Acids Res. 2017 Jun 07

Pubmed

“Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface.”

Boulay AC, Saubamea B, Adam N, Chasseigneaux S, Mazare N, Gilbert A, Bahin M, Bastianelli L, Blugeon C, Perrin S, Pouch J, Ducos B, Le Crom S, Genovesio A, Chretien F, Decleves X, Laplanche JL, Cohen-Salmon M.

Cell Discov. 2017 Mar 28

Pubmed

“An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.”

Naro C, Jolly A, Di Persio S, Bielli P, Setterblad N, Alberdi AJ, Vicini E, Geremia R, de la Grange P, Sette C
Dev Cell. 2017 Mar

Pubmed

“Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice.”

Santo J, Lopez-Herrera C, Apolit C, Bareche Y, Lapasset L, Chavey C, Capozi S, Mahuteau-Betzer F, Najman R, Fornarelli P, Lopez-Mejía IC, Béranger G, Casas F, Amri EZ, Pau B, Scherrer D, Tazi J.

Int J Obes (Lond). 2017 Mar

Pubmed

“Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.”

Schaller S, Buttigieg D, Alory A, Jacquier A, Barad M, Merchant M, Gentien D, de la Grange P, Haase G.

Proc Natl Acad Sci U S A. 2017 Mar 7

Pubmed

“Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.”

Weiss E, Rautou PE, Fasseu M, Giabicani M, de Chambrun M, Wan J, Minsart C, Gustot T, Couvineau A, Maiwall R, Hurtado-Nedelec M, Pilard N, Lebrec D, Valla D, Durand F, de la Grange P, Monteiro RC, Paugam-Burtz C, Lotersztajn S, Moreau R.

J Hepatol. 2016 Dec 28

Pubmed

“Deregulation of pre-messenger RNA splicing and rare diseases.”

de la Grange P.

Med Sci (Paris). 2016 Dec

Pubmed