“p53 deficiency induces cancer stem cell pool expansion in a mouse model of triple-negative breast tumors.” Chiche A, Moumen M, Romagnoli M, Petit V, Lasla H, Jézéquel P, de la Grange P, Jonkers J, Deugnier MA, Glukhova MA, Faraldo MM. Oncogene. 2016 Oct 24. Pubmed
“Human Embryos Created by Embryo Splitting Secrete Significantly Lower Levels of miRNA-30c.” Noli L, Capalbo A, Dajani Y, Cimadomo D, Bvumbe J, Rienzi L, Ubaldi FM, Ogilvie C, Khalaf Y, Ilic D. Stem Cells Dev. 2016 Oct 17. Pubmed
“Nuclear poly(A)-binding protein aggregates misplace a pre-mRNA outside of SC35 speckle causing its abnormal splicing.” Klein P, Oloko M, Roth F, Montel V, Malerba A, Jarmin S, Gidaro T, Popplewell L, Perie S, Lacau St Guily J, de la Grange P, Antoniou MN, Dickson G, Butler-Browne G, Bastide B, Mouly Read more…
“Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization.” Vallerand D, Massonnet G, Kébir F, Gentien D, Maciorowski Z, De la Grange P, Sigal-Zafrani B, Richardson M, Humbert S, Thuleau A, Assayag F, de Plater L, Nicolas A, Scholl S, Marangoni E, Weigand S, Roman-Roman S, Read more…
“p27Kip1 represses the Pitx2-mediated expression of p21Cip1 and regulates DNA replication during cell cycle progression.” Gallastegui E, Biçer A, Orlando S, Besson A, Pujol MJ, Bachs O. Oncogene. 2016 Jun 6. Pubmed
“Stathmin 1/2-triggered microtubule loss mediates Golgi fragmentation in mutant SOD1 motor neurons.” Bellouze S, Baillat G, Buttigieg D, de la Grange P, Rabouille C, Haase G. Mol Neurodegener. 2016 Jun 09. Pubmed
“Involvement of GATOR complex genes in familial focal epilepsies and focal cortical dysplasia” Weckhuysen S, Marsan E, Lambrecq V, Marchal C, Morin-Brureau M, An-Gourfinkel I, Baulac M, Fohlen M, Kallay Zetchi C, Seeck M, de la Grange P, Dermaut B, Meurs A, Thomas P, Chassoux F, Leguern E, Picard F, Read more…
“Control of neuronal synapse specification by a highly dedicated alternative splicing program” Traunmüller L, Gomez AM, Nguyen TM and Scheiffele P Science. 2016 May 12 Pubmed
“Interview of GenoSplice co-founders in Biotech Finances” View (in French) at: GenoSplice Biotech Finances
“GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways.” Guerenne L, Beurlet S, Said M, Gorombei P, Le Pogam C, Guidez F, de la Grange P, Omidvar N, Vanneaux V, Mills K, Mufti GJ, Sarda-Mantel L, Noguera ME, Pla M, Read more…