Scientific Literature

Latest references

Authorship on relevant publications about our technology:

• Sudemycin E influences alternative splicing and changes chromatin modifications.
Convertini P1, Shen M, Potter PM, Palacios G, Lagisetti C, de la Grange P, Horbinski C, Fondufe-Mittendorf YN, Webb TR, Stamm S.,Nucleic Acids Res. 2014 Mar 11. Pubmed
• A Gene Expression and Pre-mRNA Splicing Signature That Marks the Adenoma-Adenocarcinoma Progression in Colorectal Cancer
Pesson M, Volant A, Uguen A, Trillet K, De La Grange P, Aubry M, Daoulas M, Robaszkiewicz M, Le Gac G, Morel A, Simon B, Corcos L., PLoS One. 2014 Feb 6.Pubmed
• A dedicated microarray for in-depth analysis of pre-mRNA splicing events: application to the study of genes involved in the response to targeted anticancer therapies
Pesson M, Eymin B, De La Grange P, Simon B, Corcos L., Mol. Cancer, 2014 Jan.Pubmed
• Valproic Acid Causes Proteasomal Degradation of DICER and Influences miRNA Expression.
Zhang Z, Convertini P, Shen M, Xu X, Lemoine F, de la Grange P, Andres DA, Stamm S, PLoS One. 2013 Dec. Pubmed
• CXXC5 (Retinoid-Inducible Nuclear Factor, RINF) is a Potential Therapeutic Target in High-Risk Human Acute Myeloid Leukemia.
Astori A, Fredly H, Aloysius TA, Bullinger L, Mas VM, de la Grange P, Delhommeau F, Hagen KM, Récher C, Dusanter-Fourt I, Knappskog S, Lillehaug JR, Pendino F, Bruserud O, Oncotarget, 2013 Aug. Pubmed
• BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells.
Beurlet S, Omidvar N, Gorombei P, Krief P, Le Pogam C, Setterblad N, de la Grange P, Leboeuf C, Janin A, Noguera ME, Hervatin F, Sarda-Mantel L, Konopleva M, Andreeff M, Tu AW, Fan AC, Felsher DW, Whetton A, Pla M, West R, Fenaux P, Chomienne C, Padua RA., Blood. 2013 Aug Pubmed
• SF3B1 mutations are associated with alternative splicing in uveal melanoma.
Furney SJ, Pedersen M, Gentien D, Dumont AG, Rapinat A, Desjardins L, Turajlic S, Piperno-Neumann S, de la Grange P, Roman-Roman S, Stern MH, Marais R., Cancer Discov. 2013 Jul 16 Pubmed
• Molecular characterization of a patient presumed to have prader-willi syndrome.
Falaleeva M, Sulsona CR, Zielke HR, Currey KM, de la Grange P, Aslanzadeh V, Driscoll DJ, Stamm S., Clin Med Insights Case Rep. 2013 May 10. Pubmed
• Human Induced Pluripotent Stem Cells As a Tool to Model a Form of Leber Congenital Amaurosis.
Lustremant C, Habeler W, Plancheron A, Goureau O, Grenot L, de la Grange P, Audo I, Nandrot EF, Monville C., Cell Reprogram. 2013 May 10. Pubmed
• Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro.
SConvertini P, Zhang J, de la Grange P, Hayward L, Zhu H, Stamm S., Biochim Biophys Acta. 2013 Mar 29. Pubmed
• Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure.
Shen M, Bellaousov S, Hiller M, de La Grange P, Creamer TP, Malina O, Sperling R, Mathews DH, Stoilov P, Stamm S., Nucleic Acids Res. 2013 Feb 7. Pubmed
• hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.
Chapat C, Kolytcheff C, Le Romancer M, Auboeuf D, De La Grange P, Chettab K, Sentis S, Corbo L., EMBO J. 2013 Feb 5. Pubmed, DOI
• Gene- and exon-expression profiling reveals an extensive LPS-induced response in immune cells in patients with cirrhosis.
Sonia Gandoura, Emmanuel Weiss, Pierre-Emmanuel Rautou, Magali Fasseu, Thierry Gustot, Frédéric Lemoine, Margarita Hurtado-Nedelec, Caroline Hego, Nathalie Vadrot, Laure Elkrief, Philippe Lettéron, Zéra Tellier, Marie-Anne Pocidalo, Dominique Valla, Didier Lebrec, André Groyer, Renato C. Monteiro, Pierre de la Grange, Richard Moreau, J Hepatol. 2013 Jan 12. Pubmed, DOI
• The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling.
Moreira Sousa C, McGuire JR, Thion MS, Gentien D, de la Grange P, Tezenas du Montcel S, Vincent-Salomon A, Durr A, Humbert S., EMBO Mol Med. 2013 Jan 9. Pubmed, DOI
• Global Profiling of Alternative Splicing Events and Gene Expression Regulated by hnRNPH/F.
Wang E, Aslanzadeh V, Papa F, Zhu H, de la Grange P, Cambi F., PLoS One. 2012;7(12):e51266. Pubmed, DOI
• TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs.
Ballarino M, Jobert L, Dembélé D, de la Grange P, Auboeuf D, Tora L., Oncogene. 2012 Nov 5. Pubmed, DOI
• Lipocalin 2 (LCN2), the TNF-like receptor TWEAKR and its ligand TWEAK act downstream of NFAT1 to regulate breast cancer cell invasion.
Gaudineau B, Fougère M, Guaddachi F, Lemoine F, de la Grange P, Jauliac S., J Cell Sci. 2012 Jul 5., Pubmed, DOI
• A transcriptome signature of endothelial lymphatic cells coexists with the chronic oxidative stress signature in radiation-induced post-radiotherapy breast angiosarcomas.
Hadj-Hamou NS, Laé M, Almeida A, de la Grange P, Kirova Y, Sastre-Garau X, Malfoy B. Carcinogenesis. 2012 May 7., Pubmed
• Sperm transcriptome profiling in oligozoospermia.
Montjean D, de La Grange P, Gentien D, Rapinat A, Belloc S, Cohen-Bacrie P, Menezo Y, Benkhalifa M. J Assist Reprod Genet. 2012 Jan;29(1):3-10., DOI, Pubmed
• Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.
Fugier C, Klein AF, Hammer C, Vassilopoulos S, Ivarsson Y, Toussaint A, Tosch V, Vignaud A, Ferry A, Messaddeq N, Kokunai Y, Tsuburaya R, de la Grange P, Dembele D, Francois V, Precigout G, Boulade-Ladame C, Hummel MC, de Munain AL, Sergeant N, Laquerrière A, Thibault C, Deryckere F, Auboeuf D, Garcia L, Zimmermann P, Udd B, Schoser B, Takahashi MP, Nishino I, Bassez G, Laporte J, Furling D, Charlet-Berguerand N. Nat Med. 2011 May 29. DOI, Pubmed
• Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function.
Ramgolam K, Lauriol J, Lalou C, Lauden L, Michel L, de la Grange P, Khatib AM, Aoudjit F, Charron D, Alcaide-Loridan C, Al-Daccak R. PLoS One 2011;6(4):e18784. DOI, Pubmed

Publications using/citing our technology:

• RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation.
.Bechara EG, Sebestyén E, Bernardis I, Eyras E, Valcárcel J. Pubmed
• Argonaute proteins couple chromatin silencing to alternative splicing.
Ameyar-Zazoua M, Rachez C, Souidi M, Robin P, Fritsch L, Young R, Morozova N, Fenouil R, Descostes N, Andrau JC, Mathieu J, Hamiche A, Ait-Si-Ali S, Muchardt C, Batsché E, Harel-Bellan A. Nat Struct Mol Biol. 2012 Sep 9. DOI, Pubmed
• Mutation of a U2 snRNA Gene Causes Global Disruption of Alternative Splicing and Neurodegeneration.
Jia Y, Mu JC, Ackerman SL. Cell. 2012 Jan 20;148(1-2):296-308. DOI, Pubmed
• Identification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome.
Rajan P, Dalgliesh C, Carling PJ, Buist T, Zhang C, Grellscheid SN, Armstrong K, Stockley J, Simillion C, Gaughan L, Kalna G, Zhang MQ, Robson CN, Leung HY, Elliott DJ. PLoS One. 2011;6(12):e29088. Epub 2011 Dec 14., Pubmed
• Modeling neuronal defects associated with a lysosomal disorder using patient-derived induced pluripotent stem cells.
Lemonnier T, Blanchard S, Toli D, Roy E, Bigou S, Froissart R, Rouvet I, Vitry S, Heard JM, Bohl D. Human Molecular Genetics 2011, Jun 30. DOI, Pubmed
• Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons.
Saint-André V, Batsché E, Rachez C, Muchardt C. Nature Structural and Molecular Biology 2011, 18(3):337-44. DOI, Pubmed

Previous references

Comments are closed.