Author Archives: GenoSplice

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In Cell Discovery: Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface






“Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface.” Boulay AC, Saubamea B, Adam N, Chasseigneaux S, Mazare N, Gilbert A, Bahin M, Bastianelli L, Blugeon C, Perrin S, Pouch J, Ducos B, Le Crom S, Genovesio … Continue reading

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GenoSplice is proud to announce its recent publication in Developmental Cell: An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation






“An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.” Naro C, Jolly A, Di Persio S, Bielli P, Setterblad N, Alberdi AJ, Vicini E, Geremia R, de la Grange P, Sette C Dev … Continue reading

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In Int J Obes (Lond).: “Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice.”






“Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice.” Santo J, Lopez-Herrera C, Apolit C, Bareche Y, Lapasset L, Chavey C, Capozi S, Mahuteau-Betzer F, Najman R, Fornarelli P, Lopez-Mejía IC, Béranger G, Casas F, Amri EZ, Pau … Continue reading

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In Proc Natl Acad Sci U S A.: “Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.”






“Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.” Schaller S, Buttigieg D, Alory A, Jacquier A, Barad M, Merchant M, Gentien D, de la Grange P, Haase G. Proc Natl Acad Sci U S A. 2017 … Continue reading

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J Hepatol.: “Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.”






“Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.” Weiss E, Rautou PE, Fasseu M, Giabicani M, de Chambrun M, Wan J, Minsart C, Gustot T, Couvineau A, Maiwall R, Hurtado-Nedelec … Continue reading

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Med Sci (Paris).: “Deregulation of pre-messenger RNA splicing and rare diseases.”






“Deregulation of pre-messenger RNA splicing and rare diseases.” de la Grange P. Med Sci (Paris). 2016 Dec Pubmed

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Neuron.: “Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity.”






“Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity.” Mauger O, Lemoine F, Scheiffele P. Neuron. 2016 Nov 21 Pubmed

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Elife.: “Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3′-end processing.”






“Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3′-end processing.” La Rosa P, Bielli P, Compagnucci C, Cesari E, Volpe E, Farioli Vecchioli S, Sette C. Elife. 2016 Nov 15 Pubmed

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Neurol Genet.: “Germline and somatic mutations in the MTOR gene in focal cortical dysplasia and epilepsy.”






“Germline and somatic mutations in the MTOR gene in focal cortical dysplasia and epilepsy.” Møller RS, Weckhuysen S, Chipaux M, Marsan E, Taly V, Bebin EM, Hiatt SM, Prokop JW, Bowling KM, Mei D, Conti V, de la Grange P, … Continue reading

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Oncogene.: “p53 deficiency induces cancer stem cell pool expansion in a mouse model of triple-negative breast tumors.”






“p53 deficiency induces cancer stem cell pool expansion in a mouse model of triple-negative breast tumors.” Chiche A, Moumen M, Romagnoli M, Petit V, Lasla H, Jézéquel P, de la Grange P, Jonkers J, Deugnier MA, Glukhova MA, Faraldo MM. … Continue reading

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