Author Archives: GenoSplice

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In Nat Commun : Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane






“Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane..” Glentis A, Oertle P, Mariani P, Chikina A, El Marjou F, Attieh Y, Zaccarini F, Lae M, Loew D, Dingli F, Sirven P, Schoumacher M, Gurchenkov BG, Plodinec M, … Continue reading

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In Nucleic Acids Res : hnRNPM guides an alternative splicing program in response to inhibition of the PI3K/AKT/mTOR pathway in Ewing sarcoma cells






“hnRNPM guides an alternative splicing program in response to inhibition of the PI3K/AKT/mTOR pathway in Ewing sarcoma cells.” Passacantilli I, Frisone P, De Paola E, Fidaleo M, Paronetto MP. Nucleic Acids Res. 2017 Oct 3 Pubmed

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In Med Sci : Neurotrophic factors for motor neurons: an à la carte menu






“Neurotrophic factors for motor neurons: an à la carte menu.” Alory A, Jacquier A, Gentien D, de la Grange P, Haase G. Med Sci. 2017 Oct Pubmed

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GenoSplice presentation at the “3ème édition des Journées Scientifiques Innovations Technologiques”






GenoSplice presentation about single cell RNA-Seq bioinformatics analysis: https://webcast.in2p3.fr/container/3eme-edition-des-journees-scientifiques-innovations-technologiques

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GenoSplice at Station F!






GenoSplice offices are now located at Station F, the world’s biggest startup campus

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In Eur J Hum Genet : Detecting splicing patterns in genes involved in hereditary breast and ovarian cancer






“Detecting splicing patterns in genes involved in hereditary breast and ovarian cancer.” Davy G, Rousselin A, Goardon N, Castéra L, Harter V, Legros A, Muller E, Fouillet R, Brault B, Smirnova AS, Lemoine F, de la Grange P, Guillaud-Bataille M, … Continue reading

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In Cancer Res: Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA






“Micronuclei Frequency in Tumors Is a Predictive Biomarker for Genetic Instability and Sensitivity to the DNA Repair Inhibitor AsiDNA.” Jdey W, Thierry S, Popova T, Stern MH, Dutreix M. Cancer Res. 2017 Aug 15 Pubmed

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In Sci Rep : Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness






“Pre-therapy liver transcriptome landscape in Indian and French patients with severe alcoholic hepatitis and steroid responsiveness.” Sharma S, Maras JS, Das S, Hussain S, Mishra AK, Shasthry SM, Sharma CB, Weiss E, Elkrief L, Rautou PE, Gilgenkrantz H, Lotersztajn S, … Continue reading

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GenoSplice in pole-nsl.org






Article regarding big data in pole-nsl.org View (in French) at: Big data : Pourquoi l’industrie pharmaceutique va devoir changer

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Nucleic Acids Res: Alternative splicing of CNOT7 diversifies CCR4-NOT functions






“Alternative splicing of CNOT7 diversifies CCR4-NOT functions.” Chapat C, Chettab K, Simonet P, Wang P, De La Grange P, Le Romancer M, Corbo L. Nucleic Acids Res. 2017 Jun 07 Pubmed

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