Author Archives: GenoSplice

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Sci Rep : Both anti-inflammatory and antiviral properties of novel drug candidate ABX464 are mediated by modulation of RNA splicing

“Both anti-inflammatory and antiviral properties of novel drug candidate ABX464 are mediated by modulation of RNA splicing” Vautrin A, Manchon L, Garcel A, Campos N, Lapasset L, Laaref AM, Bruno R, Gislard M, Dubois E, Scherrer D, Ehrlich JH, Tazi … Continue reading

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Sci Adv : Iron is neurotoxic in retinal detachment and transferrin confers neuroprotection

“Iron is neurotoxic in retinal detachment and transferrin confers neuroprotection” Daruich A, Le Rouzic Q, Jonet L, Naud MC, Kowalczuk L, Pournaras JA, Boatright JH, Thomas A, Turck N, Moulin A, Behar-Cohen F, Picard E. Sci Adv. 2019 Jan 09 … Continue reading

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Breast Cancer Res : p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling

“p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling” Chiche A, Di-Cicco A, Sesma-Sanz L, Bresson L, de la Grange P, Glukhova MA, Faraldo MM, Deugnier MA. Breast Cancer Res. 2019 Jan 25 Pubmed

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Stem Cell Reports : Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia

“Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia” Domenech C, Maillard L, Rousseau A, Guidez F, Petit L, Pla M, Clay D, Guimiot F, Sanfilippo S, Jacques S, de la … Continue reading

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In J Pathol : The iron chelator deferasirox synergizes with chemotherapy to treat triple negative breast cancers

“The iron chelator deferasirox synergizes with chemotherapy to treat triple negative breast cancers” Tury S, Assayag F, Bonin F, Chateau-Joubert S, Servely JL, Vacher S, Becette V, Caly M, Rapinat A, Gentien D, de la Grange P, Schnitzler A, Lallemand … Continue reading

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In Nat Commun : Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma

“Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma” Bruno A, Labreche K, Daniau M, Boisselier B, Gauchotte G, Royer-Perron L, Rahimian A, Lemoine F, de la Grange P, Guégan J, Bielle F, Polivka M, Adam C, … Continue reading

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Happy new year 2018!

GenoSplice wishes you a happy new year 2018!

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In Nat Commun : Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1

“Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1” Cifdaloz M, Osterloh L, Graña O, Riveiro-Falkenbach E, Ximénez-Embún P, Muñoz J, Tejedo C, Calvo TG, Karras P, Olmeda D, Miñana B, Gómez-López G, Cañon E, Eyras … Continue reading

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In Nat Commun : Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane

“Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane..” Glentis A, Oertle P, Mariani P, Chikina A, El Marjou F, Attieh Y, Zaccarini F, Lae M, Loew D, Dingli F, Sirven P, Schoumacher M, Gurchenkov BG, Plodinec M, … Continue reading

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In Nucleic Acids Res : hnRNPM guides an alternative splicing program in response to inhibition of the PI3K/AKT/mTOR pathway in Ewing sarcoma cells

“hnRNPM guides an alternative splicing program in response to inhibition of the PI3K/AKT/mTOR pathway in Ewing sarcoma cells.” Passacantilli I, Frisone P, De Paola E, Fidaleo M, Paronetto MP. Nucleic Acids Res. 2017 Oct 3 Pubmed

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