GenoSplice

BCL2 Inhibition Reveals a Dendritic Cell-Specific Immune Checkpoint That Controls Tumor Immunosurveillance Liwei Zhao #, Peng Liu #, Misha Mao, Shuai Zhang, Camille Bigenwald, Charles-Antoine Dutertre, Christian H K Lehmann, Hui Pan, Nicolas Paulhan, Lukas Amon, Aitziber Buqué, Takahiro Yamazaki, Lorenzo Galluzzi, Benoit Kloeckner, Aymeric Silvin, Yuhong Pan, Hui Chen, Read more…

Loss of Dicer in newborn melanocytes leads to premature hair greying and changes in integrin expression. Juliette U Bertrand, Valérie Petit, Zackie Aktary, Pierre DE LA Grange, Nadav Elkoshi, Pierre Sohier, Véronique Delmas, Carmit Levy, Lionel Larue J Invest Dermatol. 2023 Sep 20 Pubmed

Multi-omics comparison of malignant and normal uveal melanocytes reveals molecular features of uveal melanoma. David Gentien Elnaz Saberi-Ansari Nicolas Servant Ariane Jolly Pierre de la Grange Fariba Némati Géraldine Liot Simon Saule Aurélie Teissandier Deborah Bourc’his Elodie Girard Jennifer Wong Julien Masliah-Planchon Erkan Narmanli Yuanlong Liu Emma Torun Rebecca Goulancourt Read more…

Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration Manon Allaire, Rola Al Sayegh, Morgane Mabire, Adel Hammoutene, Matthieu Siebert, Charles Caër, Mathilde Cadoux, JingHong Wan, Aida Habib, Maude Le Gall, Pierre de la Grange, Hervé Guillou, Catherine Postic, Valérie Paradis, Sophie Lotersztajn, Hélène Gilgenkrantz JHEP Rep. 2023 May Read more…

Alzheimer’s disease pathogenetic progression is associated with changes in regulated retained introns and editing of circular RNAs. Karol Andrea Arizaca Maquera, Justin Ralph Welden, Giorgi Margvelani, Sandra C Miranda Sardón, Samantha Hart, Noémie Robil, Alvaro Gonzalo Hernandez, Pierre de la Grange, Peter T Nelson, Stefan Stamm Front Mol Neurosci. 2023 Read more…

Neurofilament accumulations in amyotrophic lateral sclerosis patients’ motor neurons impair axonal initial segment integrity Cynthia Lefebvre-Omar, Elise Liu, Carine Dalle, Boris Lamotte d’Incamps, Stéphanie Bigou, Clément Daube, Léa Karpf, Marc Davenne, Noémie Robil, Coline Jost Mousseau, Stéphane Blanchard, Guillaume Tournaire, Charles Nicaise, François Salachas, Lucette Lacomblez, Danielle Seilhean, Christian S Read more…

Evidence of inter- and intra-keloid heterogeneity through analysis of dermal fibroblasts: A new insight in deciphering keloid physiopathology. Kévin Serror, Lauren Ferrero, Françoise Boismal, Maxime Sintes, Manuel Thery, Benoit Vianay, Emilie Henry, David Gentien, Pierre DE LA Grange, David Boccara, Maurice Mimoun, Jean-David Bouaziz, Armand Benssussan, Laurence Michel Exp Dermatol. Read more…

CDK12/13 promote splicing of proximal introns by enhancing the interaction between RNA polymerase II and the splicing factor SF3B1 Valentina Panzeri, Marco Pieraccioli, Eleonora Cesari, Pierre de la Grange, Claudio Sette Nucleic Acids Res. 2023 Apr 7 Pubmed

MAIT cell inhibition promotes liver fibrosis regression via macrophage phenotype reprogramming. Morgane Mabire, Pushpa Hegde, Adel Hammoutene, Jinghong Wan, Charles Caër, Rola Al Sayegh, Mathilde Cadoux, Manon Allaire, Emmanuel Weiss, Tristan Thibault-Sogorb, Olivier Lantz, Michèle Goodhardt, Valérie Paradis, Pierre de la Grange, Hélène Gilgenkrantz, Sophie Lotersztajn Nat Commun. 2023 Apr Read more…

T-cell dysregulation and inflammatory process in Gcn2 (Eif2ak4-/-) deficient rats in basal and stress conditions. Juliette Bignard, Fabrice Atassi, Olivier Claude, Maria-Rosa Ghigna, Nathalie Mougenot, Bahgat Soilih Abdoulkarim, Florence Deknuydt, Aurélie Gestin, Virginie Monceau, David Montani, Sophie Nadaud, Florent Soubrier, Frédéric Perros Am J Physiol Lung Cell Mol Physiol. 2023 Read more…