GenoSplice

CAR T-cell Entry into Tumor Islets Is a Two-Step Process Dependent on IFNγ and ICAM-1. Chahrazade Kantari-Mimoun, Sarah Barrin, Lene Vimeux, Sandrine Haghiri, Claire Gervais, Sandy Joaquina, Joerg Mittelstaet, Nadine Mockel-Tenbrinck, Ali Kinkhabwala, Diane Damotte, Audrey Lupo, Mathilde Sibony, Marco Alifano, Elisabetta Dondi, Nadège Bercovici, Alain Trautmann, Andrew D Kaiser, Read more…

Clinical and genetic spectra of 1550 index patients with hereditary spastic paraplegia. Jean-Loup Méreaux, Guillaume Banneau, Mélanie Papin, Giulia Coarelli, Rémi Valter, Laure Raymond, Bophara Kol, Olivier Ariste, Livia Parodi, Laurène Tissier, Mathilde Mairey, Samia Ait Said, Celia Gautier, Marine Guillaud-Bataille, French SPATAX clinical network; Sylvie Forlani, Pierre de la Read more…

The oncogenic kinase NEK2 regulates an RBFOX2-dependent pro-mesenchymal splicing program in triple-negative breast cancer cells. Chiara Naro, Monica De Musso, Francesca Delle Monache, Valentina Panzeri, Pierre de la Grange, Claudio Sette J Exp Clin Cancer Res. 2021 Dec 20 Pubmed

Epithelial colonization by gut dendritic cells promotes their functional diversification. Claudia A. Rivera, Violaine Randrian, Wilfrid Richer, Yohan Gerber-Ferder, Maria-Graciela Delgado, Aleksandra S. Chikina, Annika Frede, Chiara Sorini, Mathieu Maurin, Hana Kammoun-Chaari, Sara M. Parigi, Christel Goudot, Mar Cabeza-Cabrerizo, Sylvain Baulande, Sonia Lameiras, Pierre Guermonprez, Caetano Reis e Sousa, Marc Read more…

Macrophage-derived CXCL9 and CXCL11, T-cell skin homing and disease control in mogamulizumab-treated CTCL patients. Adèle de Masson, Delphine Darbord, Gabor Dobos, Marie Boisson, Marie Roelens, Caroline Ram-Wolff, Charles Cassius, Helene Le Buanec, Pierre de la Grange, Fanélie Jouenne, Baptiste Louveau, Aurélie Sadoux, Jean-David Bouaziz, Anne Marie-Cardine, Martine Bagot, Hélène Moins Read more…

BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome Petra Gorombei, Fabien Guidez, Saravanan Ganesan, Mathieu Chiquet, Andrea Pellagatti, Laure Goursaud, Nilgun Tekin, Stephanie Beurlet, Satyananda Patel, Laura Guerenne, Carole Le Pogam, Niclas Read more…

Cytogenetic and molecular abnormalities in Waldenström’s macroglobulinemia patients: correlations and prognostic impact Daphné Krzisch, Nayara Guedes, Clémentine Boccon-Gibod, Marine Baron, Clotilde Bravetti, Frédéric Davi, Marine Armand, Luce Smagghe, Jonathan Caron, Olivier A Bernard, Santos Susin, Elise Chapiro, Véronique Leblond, Florence Nguyen-Khac, Damien Roos-Weil, FILO (French Innovative Leukemia Organization) group Am Read more…

Autoimmunity affecting the biliary tract fuels the immunosurveillance of cholangiocarcinoma Juliette Paillet, Céleste Plantureux, Sarah Lévesque, Julie Le Naour, Gautier Stoll, Allan Sauvat, Pamela Caudana, Jimena Tosello Boari, Norma Bloy, Sylvie Lachkar, Isabelle Martins, Paule Opolon, Andrea Checcoli, Agathe Delaune, Noémie Robil, Pierre de la Grange, Juliette Hamroune, Franck Letourneur, Read more…

Genes coding for transcription factors involved in stem cell maintenance are repressed by TGF-β and downstream of Slug/Snail2 in COPD bronchial epithelial progenitors. Pierre de la Grange , Ariane Jolly , Charlotte Courageux , Chamseddine Ben Brahim , Pascale Leroy Mol Biol Rep. 2021 Aug 26 Pubmed

Oligodendrocyte Secreted Factors Shape Hippocampal GABAergic Neuron Transcriptome and Physiology. Elisa Mazuir, Louis Richevaux, Merie Nassar, Noémie Robil, Pierre de la Grange, Catherine Lubetzki, Desdemona Fricker, Nathalie Sol-Foulon Cereb Cortex. 2021 May 21 Pubmed