“An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.” Naro C, Jolly A, Di Persio S, Bielli P, Setterblad N, Alberdi AJ, Vicini E, Geremia R, de la Grange P, Sette C Dev Cell. 2017 Mar Pubmed
“Pharmacological modulation of LMNA SRSF1-dependent splicing abrogates diet-induced obesity in mice.” Santo J, Lopez-Herrera C, Apolit C, Bareche Y, Lapasset L, Chavey C, Capozi S, Mahuteau-Betzer F, Najman R, Fornarelli P, Lopez-Mejía IC, Béranger G, Casas F, Amri EZ, Pau B, Scherrer D, Tazi J. Int J Obes (Lond). 2017 Read more…
“Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons.” Schaller S, Buttigieg D, Alory A, Jacquier A, Barad M, Merchant M, Gentien D, de la Grange P, Haase G. Proc Natl Acad Sci U S A. 2017 Mar 7 Pubmed
“Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.” Weiss E, Rautou PE, Fasseu M, Giabicani M, de Chambrun M, Wan J, Minsart C, Gustot T, Couvineau A, Maiwall R, Hurtado-Nedelec M, Pilard N, Lebrec D, Valla D, Durand F, de Read more…
“Deregulation of pre-messenger RNA splicing and rare diseases.” de la Grange P. Med Sci (Paris). 2016 Dec Pubmed
“Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity.” Mauger O, Lemoine F, Scheiffele P. Neuron. 2016 Nov 21 Pubmed
“Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3′-end processing.” La Rosa P, Bielli P, Compagnucci C, Cesari E, Volpe E, Farioli Vecchioli S, Sette C. Elife. 2016 Nov 15 Pubmed
“Germline and somatic mutations in the MTOR gene in focal cortical dysplasia and epilepsy.” Møller RS, Weckhuysen S, Chipaux M, Marsan E, Taly V, Bebin EM, Hiatt SM, Prokop JW, Bowling KM, Mei D, Conti V, de la Grange P, Ferrand-Sorbets S, Dorfmüller G, Lambrecq V, Larsen LH, Leguern E, Read more…
“Human Embryos Created by Embryo Splitting Secrete Significantly Lower Levels of miRNA-30c.” Noli L, Capalbo A, Dajani Y, Cimadomo D, Bvumbe J, Rienzi L, Ubaldi FM, Ogilvie C, Khalaf Y, Ilic D. Stem Cells Dev. 2016 Oct 17. Pubmed
“Nuclear poly(A)-binding protein aggregates misplace a pre-mRNA outside of SC35 speckle causing its abnormal splicing.” Klein P, Oloko M, Roth F, Montel V, Malerba A, Jarmin S, Gidaro T, Popplewell L, Perie S, Lacau St Guily J, de la Grange P, Antoniou MN, Dickson G, Butler-Browne G, Bastide B, Mouly Read more…