“A transcriptome signature of endothelial lymphatic cells coexists with the chronic oxidative stress signature in radiation-induced post-radiotherapy breast angiosarcomas.” Hadj-Hamou NS, Laé M, Almeida A, de la Grange P, Kirova Y, Sastre-Garau X, Malfoy B. Carcinogenesis. 2012 May 7 Pubmed
The “Alternative pre-mRNA Splicing” book is now available at Wiley-Blackwell (ISBN: 978-3-527-32606-8). GenoSplice wrote two chapters: “Array Analysis” and “Overview of Splicing Relevant Databases”. The three co-editors of the book are Stefan Stamm (Associate Professor in the Department for Molecular and Cellular Biochemistry at the University of Kentucky), Chris Smith Read more…
Article in french about bioinformatics: Article (French)
Article: “Mutation of a U2 snRNA Gene Causes Global Disruption of Alternative Splicing and Neurodegeneration” Yichang Jia, John C. Mu, Susan L. Ackerman Cell, Vol. 148, No. 1-2. (January 2012), pp. 296-308. doi:10.1016/j.cell.2011.11.057 The article can be found here
Article: “Sperm transcriptome profiling in oligozoospermia” Montjean D, De La Grange P, Gentien D, Rapinat A, Belloc S, Cohen-Bacrie P, Menezo Y, Benkhalifa M. J Assist Reprod Genet. 2012 Jan;29(1):3-10. Epub 2011 Oct 12. DOI, Pubmed
“Modeling neuronal defects associated with a lysosomal disorder using patient-derived induced pluripotent stem cells” Thomas Lemonnier, Stephane Blanchard, Diana Toli, Elise Roy, Stephanie Bigou, Roseline Froissart, Isabelle Rouvet, Sandrine Vitry, Jean Michel M. Heard, Delphine Bohl Hum Mol Genet. 2011 Sep 15;20(18):3653-66. Epub 2011 Jun 17 DOI, Pubmed
“Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.” Fugier C, Klein AF, Hammer C, Vassilopoulos S, Ivarsson Y, Toussaint A, Tosch V, Vignaud A, Ferry A, Messaddeq N, Kokunai Y, Tsuburaya R, de la Grange P, Dembele D, Francois V, Precigout Read more…
“Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function.” Ramgolam K, Lauriol J, Lalou C, Lauden L, Michel L, de la Grange P, Khatib AM, Aoudjit F, Charron D, Alcaide-Loridan C, Al-Daccak R. PLoS One. 2011 Apr 15;6(4):e18784. DOI, Pubmed
“Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons.” Saint-André V, Batsché E, Rachez C, Muchardt C. Nat Struct Mol Biol. 2011 Mar;18(3):337-44. Epub 2011 Feb 27. DOI, Pubmed
This study published in Nature Structural & Molecular Biology was done in collaboration with University of Cambridge, Tel-Aviv University and Affymetrix. Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB. Article: “Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated Read more…